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Cost-effectiveness of abdominal aortic aneurysm repair based on aneurysm size  Kate C. Young, PhD, Nadia A. Awad, MD, Marcia Johansson, NP, David Gillespie,

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Presentation on theme: "Cost-effectiveness of abdominal aortic aneurysm repair based on aneurysm size  Kate C. Young, PhD, Nadia A. Awad, MD, Marcia Johansson, NP, David Gillespie,"— Presentation transcript:

1 Cost-effectiveness of abdominal aortic aneurysm repair based on aneurysm size 
Kate C. Young, PhD, Nadia A. Awad, MD, Marcia Johansson, NP, David Gillespie, MD, Michael J. Singh, MD, Karl A. Illig, MD  Journal of Vascular Surgery  Volume 51, Issue 1, Pages (January 2010) DOI: /j.jvs Copyright © 2010 Society for Vascular Surgery Terms and Conditions

2 Fig 1 State transition diagram. Temporary states include minor stroke, MI, bowel ischemia, infection, vessel rupture, and endoleak. Those entering a temporary state are returned to the appropriate post-EVAR or post-open surgical repair. Permanent health states include dialysis, major stroke, and amputation. EVAR, Endovascular repair; MI, myocardial infarction. Journal of Vascular Surgery  , 27-32DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Deterministic two-way sensitivity analyses show the relationship between health state preferences of living with an AAA (A) or after EVAR repair (B) and the AAA diameter for EVAR repair. EVAR of small AAAs would be cost-effective, with a willingness to pay of $100,000/QALY, when perceived health with an AAA is poor or when health is greatly improved after repair. AAA, Abdominal aortic aneurysm; EVAR, endovascular repair; QALY, quality-adjusted life-years. Journal of Vascular Surgery  , 27-32DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Probabilistic sensitivity analysis. Simultaneously sampling over a range of costs, health state preferences and probabilities demonstrated that observational management of AAAs until 5.5 cm, compared with EVAR between 4.0 cm and 5.4 cm, would be the cost-effective treatment modality about 70% of the time. AAA, Abdominal aortic aneurysm; EVAR, endovascular repair. Journal of Vascular Surgery  , 27-32DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

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