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Hierarchical Pore Structures as Highways for Enzymes and Substrates

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Presentation on theme: "Hierarchical Pore Structures as Highways for Enzymes and Substrates"— Presentation transcript:

1 Hierarchical Pore Structures as Highways for Enzymes and Substrates
Mark V. de Ruiter, Raquel Mejia-Ariza, Jeroen J.L.M. Cornelissen, Jurriaan Huskens  Chem  Volume 1, Issue 1, Pages (July 2016) DOI: /j.chempr Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Structure and Performance of Enzyme-Loaded NU-1000 and Comparison to Reference Systems (A) Schematic of zirconium-based MOF, NU-1000, for cutinase immobilization with large and small connected hexagonal channels. The large pores allow entry and immobilization of the enzymes, and small pores provide orthogonal entry and exit ports for substrates and products, i.e., as a highway. (B) Comparison of three different MOFs in terms of loading and accessibility of similar compositions and dimensions but either with only large connected channels (PCN-600) or with unconnected large and small channels (CYCU-3).4 Chem 2016 1, 29-31DOI: ( /j.chempr ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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