1. Changing to a coconut oil-containing diet reduces preexisting GI colonization by C. albicans.
Changing to a coconut oil-containing diet reduces preexisting GI colonization by C. albicans. Mice on a beef tallow-containing diet (18% by weight) were inoculated with C. albicans, and colonization was measured using fecal pellets collected on the days indicated. Fourteen days postinoculation, mice were switched to a coconut oil-containing diet (18% by weight); data from mice maintained on the beef tallow- or coconut oil-containing diet throughout the experiment are shown for comparison. Eighteen days postinoculation (4 days after the change in diet), colonization in mice switched from the beef tallow to the coconut oil diet was lower than that in mice maintained on the beef tallow diet and was not significantly different from that in mice fed the coconut oil-containing diet throughout the experiment. Data shown as geometric means ± standard errors; n = 8 to 12 mice per diet. **, P ≤ 0.01, Tukey’s HSD test.
Kearney T. W. Gunsalus et al. mSphere 2016; doi: /mSphere