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H. Zhang, M. D. , Ph. D. , K. W. Marshall, M. D. , Ph. D. , F. R. C. S

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Presentation on theme: "H. Zhang, M. D. , Ph. D. , K. W. Marshall, M. D. , Ph. D. , F. R. C. S"— Presentation transcript:

1 Profiling genes expressed in human fetal cartilage using 13,155 expressed sequence tags 
H. Zhang, M.D., Ph.D., K.W. Marshall, M.D., Ph.D., F.R.C.S. (C), H. Tang, M.Sc., D.M. Hwang, M.D., Ph.D., M. Lee, B.Sc., C.C. Liew, Ph.D.  Osteoarthritis and Cartilage  Volume 11, Issue 5, Pages (May 2003) DOI: /S (03)

2 Fig. 1 Relative expression levels of seven types of ECM proteins in human fetal cartilage. EST numbers matched to each type of ECM were summed. EST frequency was then calculated by dividing the EST copy number of each ECM into the total number of ECM ESTs (n=1056). COL, collagens; PG, proteoglycans; MATN1, matrilin 1; SPARC, secreted protein, acidic and rich in cysteine (osteonectin); CRTL1, cartilage link protein 1; FN, fibronectin. Osteoarthritis and Cartilage  , DOI: ( /S (03) )

3 Fig. 2 Relative expression levels of nine collagen genes in human fetal cartilage. Relative EST frequency level was calculated by dividing the EST copy number of each collagen gene into the total number of collagen ESTs (n=723). Osteoarthritis and Cartilage  , DOI: ( /S (03) )

4 Fig. 3 Relative expression levels of six proteoglycan genes in human fetal cartilage. Relative EST frequency level was calculated by dividing the EST copy number of each proteoglycan gene into the total number of proteoglycan ESTs (n=92). GPC3, glypican 3; DCN, decorin; AGG, aggrecan; PG4, proteoglycan 4; LUM, lumican; SDC2, syndecan 2; FMOD, fibromodulin. Osteoarthritis and Cartilage  , DOI: ( /S (03) )


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