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Volume 131, Issue 5, Pages (November 2006)

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Presentation on theme: "Volume 131, Issue 5, Pages (November 2006)"— Presentation transcript:

1 Volume 131, Issue 5, Pages 1431-1439 (November 2006)
Obesity Does Not Increase Effects of Synthetic Ghrelin on Human Gastric Motor Functions  Filippo Cremonini, Michael Camilleri, Maria Vazquez Roque, Sanna McKinzie, Duane Burton, Kari Baxter, Alan R. Zinsmeister  Gastroenterology  Volume 131, Issue 5, Pages (November 2006) DOI: /j.gastro Copyright © 2006 AGA Institute Terms and Conditions

2 Figure 1 Experimental protocol.
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2006 AGA Institute Terms and Conditions

3 Figure 2 Study flow (mean ± SD).
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2006 AGA Institute Terms and Conditions

4 Figure 3 Effects of ghrelin and placebo on plasma growth hormone (GH) response (upper panels) and on ghrelin levels (lower panels). Note the increased levels of GH (mean, 15.4 ng/mL) and ghrelin in response to injection of synthetic human ghrelin at time 0. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2006 AGA Institute Terms and Conditions

5 Figure 4 Examples of fasting gastric volume images from a subject receiving placebo and another receiving ghrelin (respective volume measurements are included). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2006 AGA Institute Terms and Conditions

6 Figure 5 Effect of ghrelin versus placebo on aggregate postprandial symptoms (maximum score, 400). Note the lack of difference in the symptom scores. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2006 AGA Institute Terms and Conditions


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