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Cecil and Ida Green Distinguished Professor
东南大学生物科学与医学工程学院 生物电子学国家重点实验室邀请 美国国家医学院院士 麻省理工学院国际著名教授来校讲学 Professor Roger D. Kamm Cecil and Ida Green Distinguished Professor Massachusetts Institute of Technology Director, NSF Science and Technology Center on Emergent Behaviors of Integrated Cellular Systems Dr. Roger D. Kamm 美国国家医学院院士, 世界生物力学学会主席 (副主席,主席,会议主席,Various duties, 1998-present) 美国生物力学学会主席(秘书长,副主席,主席)( ). A primary objective of Kamm’s research has been the application of fundamentals in fluid and solid mechanics to better understand essential biological and physiological phenomena. Studies over the past 35 years have addressed issues in the respiratory, ocular and cardiovascular systems. More recently, his attention has focused on new areas, the molecular mechanisms of cellular force sensation, cell population dynamics, and the development of new microfluidic platforms for the study of cell-cell and cell-matrix interactions, especially in the context of metastatic cancer. Kamm has been a leader in bringing the fields of mechanics together with biology and chemistry; by exploring the ways in which single molecules transmit force through macromolecular networks and the resulting change in molecular binding or enzymatic activity; and by developing new cell culture methods that enable simultaneous study of multiple cell types communicating in a realistic microenvironment. This cumulative work has led to over 280 refereed publications. Recognition for his contributions is reflected in Kamm’s election as Fellow to AIMBE, ASME, BMES, AAAS and the IFMBE. He is also the 2010 recipient of the ASME Lissner Medal and the 2015 recipient of the Huiskes Medal, both for lifetime achievements, and is a member of the Academy of Medicine. He is a member of the US National Academy of Medicine. He directs a Program Project Grant on mechanotransduction (NHLBI), a Biomechanics Training Grant, an Interdisciplinary Research Group in Singapore, and an NSF Science and Technology Center on Emergent Behaviors of Integrated Cellular Systems. Dr. Kamm is a Principal Investigator of the Bioengineering, Biological Engineering Division at M.I.T. 学术报告 Models for Human Disease: An Engineering Perspective 美国国家医学院院士, 麻省理工学院国际著名教授 Professor Roger Kamm 时间: , 2:00-3:00 PM (Mini Presentations, Q & A: 3:00-4:30 PM) 地点:四牌楼校区逸夫科技馆3楼 生物电子学国家重点实验室会议室 In this talk, I will summarize some of the various research projects from my lab over the past thirty years, spanning scales from molecular to whole organ, encompassing both computational and experimental methods, and emphasizing some of our most recent work in microfluidics. Topics will include respiratory and ocular fluid dynamics, cytoskeletal mechanics and mechanotransduction, and molecular simulation of protein aggregation and conformational change. In the context of microfluidics, I will focus on our recent work in developing microfluidic models of the different stages of metastatic cancer, and how microfluidics can be beneficial in providing new insights into the mechanisms of disease progression and in screening for effective cancer therapies.
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