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SPINK1 Is a Susceptibility Gene for Fibrocalculous Pancreatic Diabetes in Subjects from the Indian Subcontinent  Zahid Hassan, Viswananthan Mohan, Liaquat.

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Presentation on theme: "SPINK1 Is a Susceptibility Gene for Fibrocalculous Pancreatic Diabetes in Subjects from the Indian Subcontinent  Zahid Hassan, Viswananthan Mohan, Liaquat."— Presentation transcript:

1 SPINK1 Is a Susceptibility Gene for Fibrocalculous Pancreatic Diabetes in Subjects from the Indian Subcontinent  Zahid Hassan, Viswananthan Mohan, Liaquat Ali, Rebecca Allotey, Khalid Barakat, M. Omar Faruque, Raj Deepa, Michael F. McDermott, Alan E. Jackson, Paul Cassell, David Curtis, Susan V. Gelding, Shanti Vijayaravaghan, Niklaus Gyr, David C. Whitcomb, A.K. Azad Khan, Graham A. Hitman  The American Journal of Human Genetics  Volume 71, Issue 4, Pages (October 2002) DOI: /342731 Copyright © 2002 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Southern Indian family in which each individual genotyped is homozygous for the SPINK1 N34S variant. A symbol with a line through it denotes a deceased individual, an unshaded symbol denotes an unaffected individual, a black symbol denotes an individual with FCPD, a gray symbol denotes an individual with TCP, and a diagonally striped symbol denotes an individual with IGT. SPINK1 genotypes are given under the symbols; 2 = variant. The wild-type allele was not detected in genotyped individuals from this family. The American Journal of Human Genetics  , DOI: ( /342731) Copyright © 2002 The American Society of Human Genetics Terms and Conditions


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