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Volume 4, Issue 9, Pages (October 2018)

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Presentation on theme: "Volume 4, Issue 9, Pages (October 2018)"— Presentation transcript:

1 Volume 4, Issue 9, Pages 896-898 (October 2018)
Thalidomide as an effective treatment for adult multiple xanthogranuloma  Deborah Debois, MD, Liliane Marot, MD, Marc Andre, MD, PhD, Claire Dachelet, MD  JAAD Case Reports  Volume 4, Issue 9, Pages (October 2018) DOI: /j.jdcr Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Skin examination finds well-demarcated, orange-reddish nodules of 0.5 to 1 cm with a firm to elastic consistency. JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Punch biopsy result shows dense granulomatosis infiltrate composed mainly of histiocytes intermingled with collagen bundles, few neutrophils, eosinophils, and lymphocytes. (Hematoxylin-eosin stain; original magnification: ×20.) JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Strong positive reaction to CD163.
JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Complete clearance of the skin lesions 3 weeks after the beginning of the treatment based on thalidomide (50 mg once a day), leaving only hyperpigmented macules. JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions


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