1. Interaction of drug substrates and the AcrB-binding protomer analyzed with Autodock Vina docking software.
Interaction of drug substrates and the AcrB-binding protomer analyzed with Autodock Vina docking software. Substrates are shown to bind to either the upper part (groove binder) (doxorubicin [A] and tetracycline [B]) or the lower part (cave binder) (chloramphenicol [C] and cyclohexane [D]) of the distal binding site. (Modified from reference 91.)‏
Xian-Zhi Li et al. Clin. Microbiol. Rev. 2015; doi: /CMR