1. Quantitative Proteomic Analysis of Stratum Corneum Dysfunction in Adult Chronic Atopic Dermatitis 
Jason M. Winget, Deborah Finlay, Kevin J. Mills, Tom Huggins, Charles Bascom, Robert J. Isfort, Robert L. Moritz 
Journal of Investigative Dermatology 
Volume 136, Issue 8, Pages (August 2016)
DOI: /j.jid
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2. Figure 1
Fractional citrullination (modifications to arginine) for selected proteins. Many proteins related to epidermal differentiation and homeostasis decrease in citrullination with perturbation. The unrelated but highly citrullinated protein trichohyalin shows little change with condition. DCD, dermcidin; FABP5, fatty acid-binding protein, epidermal; FLG, filaggrin; FLG2, filaggrin-2; KLK5, kallikrein-5; KRTDAP, keratinocyte differentiation-associated protein; LY6D, lymphocyte antigen 6D; SERPINB13, serpin B13; TCHH, trichohyalin.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2016 The Authors Terms and Conditions

3. Figure 2
Differentially observed proteins in atopic dermatitis. (a) Differentially identified proteins (P < 0.05) from Fisher exact test. Bar lengths indicate the observations by clinical condition. Proteins with the five lowest P-values are shown for each condition. The full data table is in Supplementary Table S2 online. (b) Differentially abundant proteins (adjusted P < 0.05) for healthy versus atopic (nonlesional and lesional) samples. Bars represent the difference in average Normalized Spectral Index by clinical condition. Positive values indicate higher abundance in atopic samples and negative values indicate higher abundance in healthy samples. CARD, C-terminal caspase-recruitment domain; SIN, normalized spectral index.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2016 The Authors Terms and Conditions