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Nuclear substructure and dynamics

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Presentation on theme: "Nuclear substructure and dynamics"— Presentation transcript:

1 Nuclear substructure and dynamics
Angus I Lamond, Judith E Sleeman  Current Biology  Volume 13, Issue 21, Pages R825-R828 (October 2003) DOI: /j.cub

2 Figure 1 Fluorescence micrograph illustrating the internal compartmentalization of chromatin and nuclear bodies in mammalian cell nuclei. Scale bar=5 μm Current Biology  , R825-R828DOI: ( /j.cub )

3 Figure 2 Nuclear trafficking of newly imported snRNPs illustrated in cartoon micrographs. The GFP-labeled snRNPs accumulate first in Cajal bodies and only later in their steady state speckled and diffuse nucleoplasmic distribution. (For further details see: Sleeman, J.E. and Lamond, A.I. Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr. Biol. 9, 1065–1074.) Current Biology  , R825-R828DOI: ( /j.cub )


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