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C. E. Berger, M. D. , A. Kröner, M. D. , K. H. Kristen, M. D. , M

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Presentation on theme: "C. E. Berger, M. D. , A. Kröner, M. D. , K. H. Kristen, M. D. , M"— Presentation transcript:

1 Spontaneous osteonecrosis of the knee: biochemical markers of bone turnover and pathohistology 
C.E. Berger, M.D., A. Kröner, M.D., K.H. Kristen, M.D., M. Minai-Pour, M.D., T. Leitha, M.D., A. Engel, M.D.  Osteoarthritis and Cartilage  Volume 13, Issue 8, Pages (August 2005) DOI: /j.joca Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

2 Fig. 1 These graphs show the individual values of bone to serum ratios in patients with spontaneous ON (A) and OA (B) of the knee. (C) The graph shows the individual values of bone to serum ratios in healthy controls18. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

3 Fig. 2 Photomicrograph of an osteonecrotic lesion (stain, Giemsa, original magnification, ×40). Rupture and collapse of the articular cartilage are seen adjacent to necrotic bone in the subchondral area (arrows). Necrotic bone marrow is surrounded by fibrovascular proliferation (granulation tissue). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions


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