1. Polar body biopsy Fertility and Sterility
Markus Montag, Ph.D., Maria Köster, D.V.M., Thomas Strowitzki, M.D., Bettina Toth, M.D. 
Fertility and Sterility 
Volume 100, Issue 3, Pages (September 2013)
DOI: /j.fertnstert
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Course of laser-assisted polar body biopsy, shown in a sequence of images that were taken within a time interval of 2 minutes. After positioning of the oocytes with both polar bodies aligned in one focal plane (A), a precise opening is introduced by 2–3 laser shots (B). Through the opening a blunt biopsy capillary can be introduced to aspirate the polar bodies (C), which can then be released in a separate droplet in the same dish (D) for further processing.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Array-CGH–based PB diagnosis. (A) An example of a euploid polar body after array comparative genomic hybridization. Hybridization signals for all chromosomes are located within the standard deviation, indicative for no gains or losses. (B) A polar body with a loss of chromosome 9 and a gain for chromosomes 11 and 15, which indicates a potential gain of chromosome 9 and a loss of chromosomes 11 and 15 in the corresponding oocyte. (C) Analysis of a polar body from a translocation carrier. Besides the presence of an unbalanced translocation, visible by a gain of 2q and a loss of 4p, there is an additional loss of chromosome 7.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions