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Published byΣυντύχη Σερπετζόγλου Modified over 6 years ago
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Kinetics of the early development of uniparental human haploid embryos
María-José Escribá, Ph.D., Laura Escrich, Ph.D., Yolanda Galiana, Ph.D., Noelia Grau, Ph.D., Arancha Galán, Ph.D., Antonio Pellicer, M.D. Fertility and Sterility Volume 105, Issue 5, Pages e1 (May 2016) DOI: /j.fertnstert Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions
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Figure 1 Embryo developmental events (model A) showing direct and indirect kinetic variables. The time reference (t0) is with respect to artificial oocyte activation (AOA) in parthenotes or ICSI in androgenotes and correctly fertilized embryos. The direct kinetic variables were as follows: time of embryo cleavage to the two-, three-, four-, five-, six-, seven-, and eight-cell stages (t2, t3, t4, t5, t6, t7, t8). The indirect kinetic variables were as follows: duration of the second cell cycle of the first blastomere to cleave from the two- to the three-cell stage (cc2a = t3 − t2); duration of the second cell cycle of the second blastomere to cleave from the two- to the four-cell stage (cc2b = t4 − t2); duration of the third cell cycle of the first (cc3a = t5 − t3), second (cc3b = t6 − t4), third (cc3c = t7 − t4), and fourth (cc3d = t8 − t4) blastomeres to cleave to the five-, six-, seven-, and eight-cell stages, respectively. Fertility and Sterility , e1DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions
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