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Asymptomatic but Functional Paraganglioma of the Posterior Mediastinum

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Presentation on theme: "Asymptomatic but Functional Paraganglioma of the Posterior Mediastinum"— Presentation transcript:

1 Asymptomatic but Functional Paraganglioma of the Posterior Mediastinum
Ken Suzawa, MD, Hiromasa Yamamoto, MD, PhD, Koichi Ichimura, MD, PhD, Shinichi Toyooka, MD, PhD, Shinichiro Miyoshi, MD, PhD  The Annals of Thoracic Surgery  Volume 97, Issue 3, Pages (March 2014) DOI: /j.athoracsur Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Preoperative diagnostic imaging. (A) Contrast agent–enhanced computed tomographic scan showing hypervascular mediastinal tumor. (B) Single photon emission computed tomographic scan showing increased uptake in the mediastinal tumor. (C) Positron emission tomography computed tomographic scan showing strong uptake of 18F-fluorodeoxyglucose into the mediastinal tumor. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Histologic appearance of the tumor showing tumor cells arranged in nests (Zellballen), with no necrosis, no mitosis in high-power field, and no invasion into fibrous capsule. (Hematoxylin and eosin.) (B–D) Immunohistochemical staining of the tumor showing positivity for chromogranin (B) and synaptophysin (C) and focal positivity for protein S-100 (D). These digital images were captured with a digital camera (Olympus DP 20; Olympus) attached to a microscope (Olympus B× 51) using a ×20 objective lens. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

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