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Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function  Martin Strüber, MDa, Jens M. Hohlfeld, MDb,

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Presentation on theme: "Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function  Martin Strüber, MDa, Jens M. Hohlfeld, MDb,"— Presentation transcript:

1 Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function  Martin Strüber, MDa, Jens M. Hohlfeld, MDb, Sandra Fraund, MDa, Peter Kim, MDa, Gregor Warnecke, MSa, Axel Haverich, MDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 120, Issue 3, Pages (September 2000) DOI: /mtc Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

2 Fig. 1 Survival after reperfusion of the left lung and clamping of the right lung in percentage of animals per group. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

3 Fig. 2 PO2/FIO2 of lungs preserved with LPD and EC solution before flush perfusion (basal) and after 0.5 to 7 hours of reperfusion with clamping of the contralateral lung. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

4 Fig. 3 Dynamic compliance of lungs preserved with LPD and EC solution before flush perfusion (basal) and after 0.5 to 7 hours of reperfusion with clamping of the contralateral lung. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

5 Fig. 4 Pulmonary vascular resistance (PVR) of lungs preserved with LPD and EC solution before flush perfusion (basal) and after 0.5 to 7 hours of reperfusion with clamping of the contralateral lung. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

6 Fig. 5 Minimal surface tension of BAL fluid in milli-Newtons per meter, as determined with a bubble surfactometer. Results are shown before flush perfusion of the right lungs (basal) and after 2 hours of reperfusion of the left lungs. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

7 Fig. 6 Protein concentration of BAL fluid in milligrams per liter. Results are shown before flush perfusion of the right lungs (basal) and after 2 hours of reperfusion of the left lungs. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

8 Fig. 7 Small aggregates/large aggregates ratio of BAL fluid. Results are shown before flush perfusion of the right lungs (basal) and after 2 hours of reperfusion of the left lungs. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions


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