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Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target?  Hatem Amer, Matthew D. Griffin  Kidney International 

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Presentation on theme: "Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target?  Hatem Amer, Matthew D. Griffin  Kidney International "— Presentation transcript:

1 Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target?  Hatem Amer, Matthew D. Griffin  Kidney International  Volume 85, Issue 2, Pages (January 2014) DOI: /ki Copyright © 2014 International Society of Nephrology Terms and Conditions

2 Figure 1 Illustration of current understanding of the predisposing, causative, and common mechanistic pathways involved in the pathogenesis of interstitial fibrosis and tubular atrophy of kidney transplants in the current era. eGFR, estimated glomerular filtration rate; ER, endoplasmic reticulum; TGF-β, transforming growth factor-β. Kidney International  , DOI: ( /ki ) Copyright © 2014 International Society of Nephrology Terms and Conditions


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