1. Supplemental file 4
Disease free survivals of the entire cohort of patients A 20 40 60 80
100
Disease Free Survival (months)
Cumulative Survival (%)
Disseminated
Nasal
P = 0.001
Non-nasal B 20 40 60 80
100
Disease Free Survival (months)
Cumulative Survival (%)
P = 0.033
Stage I
Stage II
Stage IV

2. C D 20 40 60 80 100 Disease Free Survival (months)
Cumulative Survival (%)
Negative EBV DNA SMILE (I)
Positive EBV DNA SMILE (I)
P = 0.01 D 20 40 60 80
100
Disease Free Survival (months)
Cumulative Survival (%)
P < 0.001
IPI = 1
IPI = 0
IPI = 2
IPI = 3
IPI = 5

3. E 20 40 60 80 100 Disease Free Survival (months)
Cumulative Survival (%)
KIPI = 4
KIPI = 3
KIPI = 2
KIPI = 1
KIPI = 0
P = 0.024