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Natural History of Chronic Idiopathic Intestinal Pseudo-Obstruction in Adults: A Single Center Study
Vincenzo Stanghellini, Rosanna F. Cogliandro, Roberto De Giorgio, Giovanni Barbara, Antonio M. Morselli-labate, Laura Cogliandro, Roberto Corinaldesi Clinical Gastroenterology and Hepatology Volume 3, Issue 5, Pages (May 2005) DOI: /S (04) Copyright © 2005 American Gastroenterological Association Terms and Conditions
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Figure 1 Flowchart summarizing the reasons for exclusion of patients originally referred for suspected intestinal pseudo-obstruction. SB, small bowel. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions
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Figure 2 Small bowel manometric recording during fasting in a 26-year-old woman affected by CIIP. Black arrows indicate groups of uncoordinated intense contractions that are not normally propagated and occur erratically at all levels of the proximal small bowel (bursts). See reference 4 for details. Recording sites were positioned at 10-cm intervals in proximal (D1), descending (D2), and distal duodenum (D3) and in the proximal jejunum J1 and J2. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions
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Figure 3 Representative examples showing the general neuronal marker NSE (A, B) and the peptide SP/TK (C, D) immunoreactivities in the neuromuscular layer of the jejunum of a patient with CIIP (A, C) and in a control subject (B, D). Note the marked reduction of NSE and SP/TK immunoreactive neural network in the myenteric plexus and in nerve fibers targeting the muscular layer in this CIIP patient (female, 26 years old) (A, C) compared to the control (B, D). Streptavidin biotin immunoperoxidase technique. Calibration bar, 20 μm. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions
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