1. Noninvasive Diagnosis of Hepatic Fibrosis in Patients With Chronic Hepatitis C by Splenic Doppler Impedance Index 
Chen–Hua Liu, Shih–Jer Hsu, Jou–Wei Lin, Juey–Jen Hwang, Chun–Jen Liu, Pei–Ming Yang, Ming–Yang Lai, Pei–Jer Chen, Jun– Herng Chen, Jia–Horng Kao, Ding–Shinn Chen 
Clinical Gastroenterology and Hepatology 
Volume 5, Issue 10, Pages e1 (October 2007)
DOI: /j.cgh
Copyright © 2007 AGA Institute Terms and Conditions

2. Figure 1 Flow diagram of the study.
Clinical Gastroenterology and Hepatology 2007 5, e1DOI: ( /j.cgh )
Copyright © 2007 AGA Institute Terms and Conditions

3. Figure 2
DDU images to evaluate (A) PVVmean, (B) HARI and HAPI of the right branch of the hepatic artery, and (C) SARI and SAPI of the splenic artery near the splenic hilum.
Clinical Gastroenterology and Hepatology 2007 5, e1DOI: ( /j.cgh )
Copyright © 2007 AGA Institute Terms and Conditions

4. Figure 3
ROC curves of regression models, SAPI, and PVVmean in predicting patients with significant hepatic fibrosis (≥F2) and cirrhosis (F4) in the training set. (A) AUCs of the regression model and SAPI were comparable in predicting patients with significant hepatic fibrosis (0.88 vs 0.87, P = .22). In addition, AUCs of the regression model and SAPI were higher than PVVmean in predicting patients with significant hepatic fibrosis (0.88 vs 0.70, P < .001, and 0.87 vs 0.70, P < .001, respectively). (B) AUCs of the regression model and SAPI were comparable in predicting patients with cirrhosis (0.92 vs 0.90, P = .12). In addition, AUCs of the regression model and SAPI were higher than PVVmean in predicting patients with significant hepatic fibrosis (0.92 vs 0.80, P < .001, and 0.90 vs 0.80, P = .03, respectively).
Clinical Gastroenterology and Hepatology 2007 5, e1DOI: ( /j.cgh )
Copyright © 2007 AGA Institute Terms and Conditions

5. Figure 4
ROC curves of regression models, SAPI, and PVVmean in predicting patients with significant hepatic fibrosis (≥F2) and cirrhosis (F4) in the validation set. (A) AUCs of the regression model and SAPI were comparable in predicting patients with significant hepatic fibrosis (0.89 vs 0.89, P = .37). In addition, AUCs of the regression model and SAPI were higher than PVVmean in predicting patients with significant hepatic fibrosis (0.89 vs 0.74, P < .001, and 0.89 vs 0.74, P < .001, respectively). (B) AUCs of the regression model and SAPI were comparable in predicting patients with cirrhosis (0.93 vs 0.92, P = .30). In addition, AUCs of regression model and SAPI were higher than PVVmean in predicting patients with significant hepatic fibrosis (0.93 vs 0.78, P < .001, and 0.92 vs 0.78, P = .004, respectively).
Clinical Gastroenterology and Hepatology 2007 5, e1DOI: ( /j.cgh )
Copyright © 2007 AGA Institute Terms and Conditions