1. Thursday, November 3, 2016 Test next Wednesday!
Cancer Reading Assignment Due
Immortal Cancer Cells - #6 STAMP
Cancer Sniffing Dog - #7 STAMP
PLACE ON CORNER OF DESK
Grab notes from entry table.
Test next Wednesday!

2. Bell-Ringer 11/7 Place your phone in a pocket!!!! Muahahahaha
Complete the DNA: The Molecule of Heredity paper.
Complete the DNA Replication paper.

3. What do all these organisms have in common?
Mushroom
Jellyfish
Diatoms
Shark
DNA
Flower
Panda Bear
Algae
Venus Fly Trap
E. coli

4. DNA
We will describe the structure of DNA molecule, DNA replication, and the scientists who contributed to the research and discovery of DNA.
I will create a complementary base pairs to the given DNA strand.

5. What is DNA? https://www.youtube.com/watch?v=1YDTOcAVJrE

6. DNA FUN FACTS

7. 600
Your DNA could stretch from the earth to the sun 600 times.

8. 99.9%
We’re all 99.9 percent alike

9. 3 Billion = 3,000,000,000
The human genome contains 3 billion base pairs of DNA.

10. 3%
Only 3% of your genes (DNA) are useful the rest of 97% are considered “Junk” DNA.

11. 50%
Bananas and humans share about half of the same DNA which means humans are 50% identical to bananas.

12. DNA scientists to know
Rosalind Franklin – Discovered the structure of DNA using X-ray Diffraction

13. DNA scientists to know James Watson and Francis Crick-
Created a 3D model of DNA and described the DNA as Double Helix and two strands that folds in twisted ladder.

14. Erwin Chargaff (1950)
1950, formation of “Chargaff’s Rules” which are as follows:
Number of adenine or A are always equal to the number of thymine or T
Number of guanine or G are always equal to the number of cytosine or C

15. DNA Base Pairing Rules Chargaff’s rule: % of A = % of T % of C= % of G
Adenine pairs with Thymine
Guanine pairs with Cytosine
A-T; G-C
“Cars are parked in the Garage”
“Apple grows on Trees”

16. Find the complementary sequence to the following “A-A-T-C-C-G-A-T-A-G-C”
T-T-A-G-G-C-T-A-T-C-G
C-C-A-G-G-A-C-T-C-G-C
T-T-A-G-G-C-T-T-T-G-C A

17. DNA Scientists

18. What is the complimentary DNA strand: 5’ATGCCATAGCCT3’
Bell-Ringer 11/4
What is the complimentary DNA strand:
5’ATGCCATAGCCT3’

19. 11/2-PHONES IN POCKETS
Glue the DNA Labeling paper into your journal, and begin working on it!
QUIZ RE-TAKES Friday-Tuesday (BEFORE SCHOOL or AFTER SCHOOL)
DNA SCIENTIST AND STRUCTURE QUIZ TOMORROW!

20. DNA- Deoxyribonucleic Acid

21. What does the shape of DNA look like?or
comb
Ladder

22. Structure of DNA The structure of DNA is known as Double Helix
The structure of DNA is known as Double Helix
Which means that it is a Double strand folded in Twisted Ladder

23. What is DNA? DNA= Genetic code of life
DNA is the Universal code, common to all living organisms.
DNA contains Genetic information of an organism.
Genes: Sections of DNA that codes for specific cell function.

24. DNA is found in: Nucleus of Eukaryotes Chloroplast
Cytoplasm of Prokaryotes
Mitochondria
Chloroplast

25. Parts of DNA

26. “Peanut butter Sandwich”
Parts of a Nucleotide
DNA belongs to the biomolecule: Nucleic Acid
DNA is made of subunits called Nucleotide
Which is made up of Phosphate group, Deoxyribose Sugar, and Nitrogenous Base.
“Peanut butter Sandwich”

27. Parts of a Nucleotide Nitrogenous Base Sugar Phosphate group
(Deoxyribose)

28. If DNA looks like a ladder then…
What 2 parts makes the backbone of DNA?
What parts make the rung?
What bond (H-bond) holds the rungs together?
backbone
Rung

29. Parts of DNA Phosphate group & Deoxyribose Sugar
The backbone of DNA ladder is made of:
Phosphate group & Deoxyribose Sugar
The rungs of DNA are made of: Nitrogenous Bases
There are 4 nitrogenous bases: Adenine, Thymine, Guanine, Cytosine
(A pairs with T and G pairs with C)
The bases are held together by Hydrogen Bond

30. Nitrogen bases= codes for our trait
There are 4 letters in the DNA sequence
ATA CGC= nail protein

31. DNA Base Pairing Rules- (Bottom left tab)
Chargaff’s rule:
% of A = % of T
% of C= % of G
Adenine pairs with Thymine
Guanine pairs with Cytosine
A-T; G-C
“Cars are parked in the Garage”
“Apple grows on Trees”

32. Questions?

33. DNA Replication Replication= Copying
The DNA Replication model is known as Semi conservative Model
Meaning you get 1OLD strand and 1 New strand
Old
New
Old
New

34. DNA Replication Hydrogen bonds are unzipped by DNA helicase.
Replication fork-site of DNA unzipping
DNA replication occurs in 5’ (prime) to 3’ (prime) direction.
DNA polymerase pairs free nucleotides to each original unzipped strand.

35. RESULT: Two identical strands of DNA
Leading Strand: Replication in the same direction as replication fork 
Lagging strand: Replication away from the replication fork
Also known as Okazaki Fragment

36. DNA Replication

37. 11/3-PHONES IN POCKETS FOR QUIZ!
Begin working on the Genes & Chromosomes warm-up, and glue into your journal.
Cell Cycle Quiz Re-Takes: Today-Tuesday!
DNA Replication Quiz on Monday!

38. Phosphate Group: Green Deoxyribose Sugar: Purple Thymine: Yellow
DNA Replication
Phosphate Group: Green
Deoxyribose Sugar: Purple
Thymine: Yellow
Adenine: Pink
Cytosine: Red
Guanine: Blue