1. Volume 11, Issue 7, Pages 927-938 (July 2004)
The Biosynthetic Gene Cluster for a Monocyclic β-Lactam Antibiotic, Nocardicin A 
Michele Gunsior, Steven D Breazeale, Amanda J Lind, Jacques Ravel, James W Janc, Craig A Townsend 
Chemistry & Biology 
Volume 11, Issue 7, Pages (July 2004)
DOI: /j.chembiol

2. Figure 1 The Nocardicin Family of Antibiotics
Chemistry & Biology  , DOI: ( /j.chembiol )

3. Figure 2 Preferred Biosynthetic Route to Nocardicin A
Chemistry & Biology  , DOI: ( /j.chembiol )

4. Figure 3 Schematic Diagram of the Nocardicin A Cluster
Genes colored in green denote pHPG biosynthesis; yellow, regulation and resistance; orange, tailoring enzymes; blue, nonribosomal peptide synthetases; and light blue, genes of unknown function. The domain architecture of NocA and NocB is shown enlarged beneath the cluster map. The black and gray arrows indicate the location of the repeat sequences in NocA. The green and red arrows indicate N termini of the 200 kDa and 150 kDa proteins isolated from wild-type N. uniformis, respectively.
Chemistry & Biology  , DOI: ( /j.chembiol )

5. Figure 4
Disruption and Complementation of the nat Gene and HPLC Analysis
Chromatograms of supernatants from (A) wild-type N. uniformis, (B) disruption mutant nat::tsr, and (C) complementation mutant pAJL3248 nat::tsr are shown. Nocardicin G (*) and nocardicin A (•) peaks were confirmed by coinjection of authentic material. Inset: Disruption of nat in the plasmid pAJL3118 with the thiostrepton resistance cassette.
Chemistry & Biology  , DOI: ( /j.chembiol )

6. Figure 5 Proposed Formation of Hydroxamate and Tripeptide
Chemistry & Biology  , DOI: ( /j.chembiol )