1. Group 3 Group 3 The “Omes” Precision Cancer Medicine
Advocate Mentor: Patrick Sullivan
Scientific Mentor: Camille Ragin, PhD, MPH Group Members: Ivy Elkins, Kathye D. Jenkins, David Makumi, Katie Parker, Seana Roubinek, Lanette Veres

2. Definitions & Application
What are Omics?
Definitions & Application
Omics aims at the collective characterization and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms.
Multi-OMICS approaches in cancer can be used to:
- to dissect the cell response to chemo- or immunotherapy
-discover molecular candidates with diagnostic/prognostic value. 
Diverse OMICs strategies in cancer are important for better understanding of:
-Cancer progression,
-Discovery of new therapeutic interventions.
-Development of new cancer biomarkers

3. Banner here
Genome
Epigenome
Transcriptome
Proteome

4. Tomato
Potato

5. EGFR ALK ROS1 BRAF NTRK MET MEK
Precision Medicine Success
Molecular profiling has changed lung cancer treatment from a one-size-fits-all approach to targeted therapy for many mutations types, including:
EGFR ALK ROS1 BRAF NTRK MET MEK

6. Some examples of cancers with targeted therapies
Ovarian – PARP Inhibitors
Breast Cancer – Herceptin
CML & GIST – Gleevac

7. Examples of tumors that lend themselves to Precision Medicine Do Don’t Lung Hard to get at tissues Breast Some blood cancers CML Brain Melanoma

8. Obstacles to Precision Medicine Cost Availability Accessible Drugs Disparities Lengthy development Approval of new indications Access to clinical trials

9. Innovations/New Ideas Approaches that target multiple truncal mutations Single cell sequencing

10. Thank you for the opportunity to participate in the Scientist Survivor Program, AACR ! Love, Group 3