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Neuromuscular monitoring and postoperative residual curarisation: a meta-analysis
M. Naguib, A.F. Kopman, J.E. Ensor British Journal of Anaesthesia Volume 98, Issue 3, Pages (March 2007) DOI: /bja/ael386 Copyright © 2007 British Journal of Anaesthesia Terms and Conditions
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Fig 1 Effect of using an intraoperative neuromuscular function monitor on the incidence of PORC in patients who received long-acting neuromuscular blocking drugs. PORC is typically considered present in patients with a TOF ratio of < 0.7 (upper panel) or < 0.9 (lower panel). The position of each symbol indicates the incidence rate of PORC of each respective study. The horizontal dotted-line indicates the 95% confidence interval of each study. British Journal of Anaesthesia , DOI: ( /bja/ael386) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions
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Fig 2 Effect of using an intraoperative neuromuscular function monitor on the incidence of PORC in patients who received intermediate-acting neuromuscular blocking drugs. PORC is typically considered present in patients with a TOF ratio of < 0.7 (upper panel) or < 0.9 (lower panel). The position of each symbol indicates the incidence rate of PORC of each respective study. The horizontal dotted-line indicates the 95% confidence interval of each study. British Journal of Anaesthesia , DOI: ( /bja/ael386) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions
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Fig 3 Random-effects weighted regression for the incidence of PORC by year of study. PORC is typically considered present in patients with a TOF ratio of < 0.7 (upper panel) or < 0.9 (lower panel). For studies associating PORC by a TOF of < 0.7, neither long-acting (P = 0.52) nor intermediate-acting (P = 0.97) neuromuscular blocking drugs exhibited a significant relationship. For studies associating PORC by a TOF of < 0.9, intermediate-acting muscle relaxants showed an insignificant (P = 0.09) decrease in PORC incidence over time. There was no change in the average rates of PORC over time among studies of long-acting neuromuscular blocking drugs (P = 0.69). The size of symbols reflects the size of study. The larger the letter, the larger is number of patients included in the study. British Journal of Anaesthesia , DOI: ( /bja/ael386) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions
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