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TGFβ signaling activity in smooth muscle cells in human left main coronary arteries with various degrees of atherosclerosis TGFβ signaling activity in.

Published byΠαρθενιά Σπανού Modified over 5 years ago

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Presentation on theme: "TGFβ signaling activity in smooth muscle cells in human left main coronary arteries with various degrees of atherosclerosis TGFβ signaling activity in."— Presentation transcript:

1 TGFβ signaling activity in smooth muscle cells in human left main coronary arteries with various degrees of atherosclerosis TGFβ signaling activity in smooth muscle cells in human left main coronary arteries with various degrees of atherosclerosis A, BRepresentative images of immunofluorescence staining for TGFβ (red) from patients with no/mild, moderate, or severe disease. Nuclei were counterstained with DAPI (blue). Scale bar: 16 μm. Medial TGFβ area is shown in (B) (***P < 0.001 compared to no/mild disease; one‐way ANOVA with Newman–Keuls post hoc test for multiple comparison correction).C, DRepresentative images of immunofluorescence staining for p‐Smad2 (red) from patients with no/mild, moderate, or severe disease. Nuclei were counterstained with DAPI (blue). Scale bar: 16 μm (***P < 0.001 compared to no/mild disease; one‐way ANOVA with Newman–Keuls post hoc test for multiple comparison correction).E, FRepresentative images of immunofluorescence staining for p‐Smad3 (red) from patients with no/mild, moderate, or severe disease. Nuclei were counterstained with DAPI (blue). Scale bar: 16 μm (***P < 0.001 compared to no/mild disease; one‐way ANOVA with Newman–Keuls post hoc test for multiple comparison correction).Data information: The data shown in (D, F) are the means ± SD of the percentage of medial p‐Smad2 or p‐Smad3‐positive SMCs. Images are representative of 10 No/mild, 9 moderate, and 10 severe disease human left main coronary artery samples. A full table of P‐values for this figure is shown in Appendix Table S1. Pei‐Yu Chen et al. EMBO Mol Med. 2016;8: © as stated in the article, figure or figure legend

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