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Genotype, Phenotype and T Cell Counts at One Year Predict Survival and Long Term Immune Reconstitution after Transplantation in Severe Combined Immune.

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Presentation on theme: "Genotype, Phenotype and T Cell Counts at One Year Predict Survival and Long Term Immune Reconstitution after Transplantation in Severe Combined Immune."— Presentation transcript:

1 Genotype, Phenotype and T Cell Counts at One Year Predict Survival and Long Term Immune Reconstitution after Transplantation in Severe Combined Immune Deficiency (SCID)—The Primary Immune Deficiency Treatment Consortium (PIDTC)  Elie Haddad, Brent R. Logan, Linda M. Griffith, Rebecca H. Buckley, Roberta E. Parrott, Christopher C. Dvorak, Jennifer Puck, Susan E. Prockop, Neena Kapoor, Hisham Abdel-Azim, Imelda C. Hanson, Caridad Martinez, Jack Bleesing, Sharat Chandra, Angela R. Smith, Sung-Yun Pai, Soma Jyonouchi, Kathleen Sullivan, Ann E. Haight, Audrey G. Tumlin, Lauri Burroughs, Blachy J. Davila Saldana, Christine Seroogy, Aleksandra Petrovic, David C. Shyr, Troy C. Quigg, Alfred P. Gillio, Helene Decaluwe, Morris Kletzel, Alan Knutsen, Theodore B. Moore, Victor Aquino, Jeffrey H. Davis, Lolie C. Yu, Elizabeth M. Kang, Marlis L. Schroeder, Evan Shereck, John A. Craddock, James A. Connelly, Jeffrey J. Bednarski, Frederick Goldman, Matthew H. Porteus, Thomas Fleisher, Donald B. Kohn, Harry L. Malech, Michael A. Pulsipher, William Shearer, Paul Szabolcs, Monica Thakar, Mark Vander Lugt, Ziyan Yin, Luigi D. Notarangelo, Morton J. Cowan, Richard J. O'Reilly  Biology of Blood and Marrow Transplantation  Volume 23, Issue 3, Pages S133-S134 (March 2017) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Survival in non-MSD patients compared by genotype.
Biology of Blood and Marrow Transplantation  , S133-S134DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Landmark analysis: Overall Survival by CD4 count at 1 yr.
Biology of Blood and Marrow Transplantation  , S133-S134DOI: ( /j.bbmt ) Copyright © Terms and Conditions

4 Figure 3 ROC curve for prediction of composite measure of long-term immune reconstitution using CD4 count at 1 yr. Biology of Blood and Marrow Transplantation  , S133-S134DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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