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Interferon beta-1a–induced morphea

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Presentation on theme: "Interferon beta-1a–induced morphea"— Presentation transcript:

1 Interferon beta-1a–induced morphea
Spencer A. Bezalel, BS, Bruce E. Strober, MD, PhD, Katalin Ferenczi, MD  JAAD Case Reports  Volume 1, Issue 1, Pages (January 2015) DOI: /j.jdcr Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Depressed, indurated, bound-down hyperpigmented plaques involving anterior thighs (A) and right hip (B). JAAD Case Reports 2015 1, 15-17DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, Punch biopsy from the right thigh shows thickened collagen bundles extending into the subcutaneous fat, paucity of adnexal structures, and a deep reticular lymphocytic infiltrate (Hematoxylin-eosin stain; original magnification: ×4). B, Higher magnification image shows thickened collagen, lymphoplasmacytic infiltrate, and entrapment of the eccrine glands by collagen (original magnification: ×20). JAAD Case Reports 2015 1, 15-17DOI: ( /j.jdcr ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions


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