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Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low- dose methotrexate  Sarah Mattessich, BS, Katalin Ferenczi, MD, Jun.

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Presentation on theme: "Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low- dose methotrexate  Sarah Mattessich, BS, Katalin Ferenczi, MD, Jun."— Presentation transcript:

1 Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low- dose methotrexate  Sarah Mattessich, BS, Katalin Ferenczi, MD, Jun Lu, MD  JAAD Case Reports  Volume 3, Issue 5, Pages (September 2017) DOI: /j.jdcr Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Clinical presentations of multiple erythematous indurated plaques and subcutaneous nodules on the lower back (A), leg (B), and dorsal foot (C). JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Histologic examination. A, Deep dermal and subcutaneous infiltrate. B, Septal thickening and inflammation with lobular spilling of the infiltrate. C, Vessel wall infiltration by inflammatory cells with luminal obliteration and adjacent eosinophil-rich infiltrate. (A, Hematoxylin-eosin stain; original magnifications: A, ×10; B, ×20; C, ×40.) JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Complete resolution of vasculitis and panniculitis after low-dose methotrexate treatment. JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions


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