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Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD 

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Presentation on theme: "Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD "— Presentation transcript:

1 Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically 
Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD  The Annals of Thoracic Surgery  Volume 68, Issue 5, Pages (November 1999) DOI: /S (99)

2 Fig 1 Location of lymph node metastases by nodal station for right-sided (A) (n = 54) and left-sided (B) (n = 55) resections. The nomenclature for lymph node stations is that used for non-small cell lung cancer [10] and esophageal cancer [11]. Most patients who had lymph node metastases had more than one nodal station involved, so the number of metastatic sites exceeds the number of resections. The Annals of Thoracic Surgery  , DOI: ( /S (99) )

3 Fig 2 The relationship between tumor T status and overall survival by univariate analysis. When considered across all four categories, T status had a highly significant effect on survival (p < 0.01). The Annals of Thoracic Surgery  , DOI: ( /S (99) )

4 Fig 3 Univariate analysis of the relationship between the number of positive lymph nodes and overall survival. Patients who had four or more positive nodes had a significantly worse survival (p < 0.01). The Annals of Thoracic Surgery  , DOI: ( /S (99) )

5 Fig 4 Overall survival of all 231 patients by stage. When analyzed across all four categories, stage had a highly significant effect on survival (p < 0.01). The Annals of Thoracic Surgery  , DOI: ( /S (99) )

6 Fig 5 Comparison of the overall survival rates of patients who received adjuvant therapy versus those who did not, showing that adjuvant therapy was associated with a significantly better outcome (p < 0.01). The Annals of Thoracic Surgery  , DOI: ( /S (99) )

7 Fig 6 Overall survival analyzed according to the type of surgical procedure performed. There was no significant difference between patients who had all gross tumor removed via extrapleural pneumonectomy versus pleurectomy/decortication. The Annals of Thoracic Surgery  , DOI: ( /S (99) )


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