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Role of vitamin D receptor activators on cardiovascular risk

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Presentation on theme: "Role of vitamin D receptor activators on cardiovascular risk"— Presentation transcript:

1 Role of vitamin D receptor activators on cardiovascular risk
Jose M. Valdivielso, Juan C. Ayus  Kidney International  Volume 74, Pages S44-S49 (December 2008) DOI: /ki Copyright © 2008 International Society of Nephrology Terms and Conditions

2 Figure 1 Proposed mechanism for effects of vitamin D on left ventricular hypertrophy. Kidney International  , S44-S49DOI: ( /ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions

3 Figure 2 Effect of calcitriol or paricalcitol on LVH in hemodialysis patients receiving short daily hemodialysis for 12 months. LVH, left ventricular hypertrophy. Kidney International  , S44-S49DOI: ( /ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions

4 Figure 3 Effect of the in vivo treatment of 5/6 nephrectomized rats with calcitriol or paricalcitol on aortic calcification. Representative photographs of Von Kossa staining of (a) control animals, (b) animals treated with paricalcitol, or (c) animals treated with calcitriol. (d) Quantification of calcified areas in the aorta. Data are percentage of the media presenting calcification. (e) Quantification of calcium in the aorta. Data are μg of calcium per mg of protein. Data are mean±s.e.m. *P<0.01 vs control. Reproduced from Cardus et al.67 with permission of the American Society for Bone and Mineral Research. Kidney International  , S44-S49DOI: ( /ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions


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