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Joshua M. Rosenblum, MD, PhD, Bradley G. Leshnower, MD, Rena C

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Presentation on theme: "Joshua M. Rosenblum, MD, PhD, Bradley G. Leshnower, MD, Rena C"— Presentation transcript:

1 Durability and safety of David V valve-sparing root replacement in acute type A aortic dissection 
Joshua M. Rosenblum, MD, PhD, Bradley G. Leshnower, MD, Rena C. Moon, MPH, Yi Lasanajak, PhD, Jose Binongo, PhD, LaRonica McPherson, RN, Edward P. Chen, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 157, Issue 1, Pages e1 (January 2019) DOI: /j.jtcvs Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Kaplan–Meier all-cause survival analysis of valve-sparing root replacement (VSRR; red) and aortic root replacement with composite valved-conduit (ROOT; blue) patients. Shaded areas indicate 95% confidence intervals, with numbers at the bottom of the figure showing numbers at risk for the given time points. VSRR versus ROOT hazard ratio for death, (95% confidence interval, ); P = .004. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Cumulative incidence of aortic valve reintervention (A), echocardiographic evidence of >2+ aortic insufficiency (AI; B), and distal aortic reintervention (C) in valve-sparing root replacement (VSRR; red) and aortic root replacement with composite valved-conduit (ROOT; blue) groups. Shaded areas indicate 95% confidence intervals, with numbers at the bottom of the figure showing numbers at risk for the given time points. ECHO, Echocardiographic. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Competing risk analysis for risk of death (red line), echocardiographic evidence of >2+ aortic insufficiency (AI) or valve reintervention (green line), and event-free survival (blue line) in aortic root replacement with composite valved-conduit (ROOT; A) and valve-sparing root replacement (VSRR; B) patient groups. ECHO, Echocardiographic. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

5 Figure E1 Echocardiographic evidence of aortic insufficiency (AI) in each patient at the time points listed in aortic root replacement with composite valved-conduit (ROOT; left panel) and valve-sparing root replacement (VSRR; right panel) patients. Each line represents a single patient. Preop, Preoperative; Postop, postoperative. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

6 Incidence of aortic valve reintervention in VSRR and ROOT patients.
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

7 The Journal of Thoracic and Cardiovascular Surgery 2019 157, 14-23
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

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