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Figure 1. Mean log10 cfu/mL versus time profile for each individual drug at 4× MIC against the four VRE ... Figure 1. Mean log<sub>10</sub> cfu/mL versus time profile for each individual drug at 4× MIC against the four VRE (a–d) and E. faecalis strain (e). Curves represent average concentrations for triplicate experiments. Each antibiotic is illustrated as follows: ceftriaxone, dashed line with open diamonds; daptomycin, dashed line with open crosses; gentamicin, dashed line with open circles; linezolid, dashed line with open triangles; rifampicin, dashed line with open squares; and oritavancin, dashed line with open stars. The growth control strain is illustrated by a solid line with crosses. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( J Antimicrob Chemother, Volume 74, Issue 5, 08 February 2019, Pages 1300–1305, The content of this slide may be subject to copyright: please see the slide notes for details.
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Figure 2. Mean log10 cfu/mL versus time profile for each individual drug and combination at ¼× MIC against ... Figure 2. Mean log<sub>10</sub> cfu/mL versus time profile for each individual drug and combination at ¼× MIC against the four VRE (a–d) and E. faecalis strain (e). Curves represent average concentrations for triplicate experiments. Each antibiotic alone is illustrated as follows: ceftriaxone, dashed line with open diamonds; daptomycin, dashed line with open crosses; gentamicin, dashed line with open circles; linezolid, dashed line with open triangles; rifampicin, dashed line with open squares; and oritavancin, dashed line with open stars. Each antibiotic in combination with oritavancin is illustrated as follows: ceftriaxone, solid line with filled diamonds; daptomycin, solid line with filled crosses; gentamicin, solid line with filled circles; linezolid, solid line with filled triangles; rifampicin, solid line with filled squares; and oritavancin, solid line with filled stars. The growth control strain is illustrated by a solid line with crosses. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( J Antimicrob Chemother, Volume 74, Issue 5, 08 February 2019, Pages 1300–1305, The content of this slide may be subject to copyright: please see the slide notes for details.
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