1. The management of CKD: A look into the future
A. Khwaja, M. El Kossi, J. Floege, M. El Nahas 
Kidney International 
Volume 72, Issue 11, Pages (December 2007)
DOI: /sj.ki
Copyright © 2007 International Society of Nephrology Terms and Conditions

2. Figure 1
The cellular mechanisms underlying this fibrotic process are characterized by kidney cell loss through necrosis and apoptosis, EMT (reversal to an embryonic phenotype), and proliferation of myofibroblasts with subsequent increased ECM synthesis along with decreased breakdown and clearance of ECM.
Kidney International  , DOI: ( /sj.ki )
Copyright © 2007 International Society of Nephrology Terms and Conditions