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Published byAmanda Kovács Modified over 5 years ago
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Comparing two low-energy diets for the treatment of knee osteoarthritis symptoms in obese patients: a pragmatic randomized clinical trial B.F. Riecke, R. Christensen, P. Christensen, A.R. Leeds, M. Boesen, L.S. Lohmander, A. Astrup, H. Bliddal Osteoarthritis and Cartilage Volume 18, Issue 6, Pages (June 2010) DOI: /j.joca Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions
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Fig. 1 Progress of participants through CAROT-study. Abbreviations: ITT, Intention-to-treat population. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions
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Fig. 2 Clinical efficacy following 16 weeks therapy. A: Proportion of patients loosing ≥10% of their body weight after 8 and 16 weeks. B: Proportion of patients responding to therapy according to the OMERACT–OARSI responder criterion after 8 and 16 weeks. ▴=VLED, ■=LED. A response according to the guidelines of the OMERACT–OARSI was classified as a high improvement in pain or function (≥50%) and an absolute change≥20%, or an improvement in at least 2 of the 3 following: pain≥20% and absolute change≥10%; function≥20% and absolute change≥10%; patient's global assessment≥20% and absolute change≥10%. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions
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