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Progression of fibrosis in chronic hepatitis C

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Presentation on theme: "Progression of fibrosis in chronic hepatitis C"— Presentation transcript:

1 Progression of fibrosis in chronic hepatitis C
Marc G. Ghany, David E. Kleiner, Harvey Alter, Edward Doo, Farooq Khokar, Kittichai Promrat, David Herion, Yoon Park, T.Jake Liang, Jay H. Hoofnagle  Gastroenterology  Volume 124, Issue 1, Pages (January 2003) DOI: /gast Copyright © 2003 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Mean rate of worsening scores for fibrosis per year between 2 liver biopsies according to (A) patient age at initial liver biopsy (by every 15 years), (B) initial ALT level (n = 118; by fold elevation above the upper limit of normal), and (C) initial reading for periportal necrosis and inflammation (0–1, no or mild piecemeal necrosis; 3–4, moderate or marked piecemeal necrosis; 5–6, moderate or marked piecemeal necrosis plus bridging necrosis; 10, multilobular necrosis). The Knodell scores for lobular and portal inflammation are not included in this figure; hence, the maximal score is 10 and not 18. Gastroenterology  , DOI: ( /gast ) Copyright © 2003 American Gastroenterological Association Terms and Conditions


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