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Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic.

Published byRezső Pásztor Modified over 5 years ago

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Presentation on theme: "Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic."— Presentation transcript:

1 Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial  Richard J. Powell, MD, Phillip Goodney, MD, Farrell O. Mendelsohn, MD, Elaine K. Moen, MD, Brian H. Annex, MD  Journal of Vascular Surgery  Volume 52, Issue 6, Pages (December 2010) DOI: /j.jvs Copyright © 2010 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Example of severity of tissue loss in two patients enrolled into HGF-0205 Trial. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Toe brachial index at baseline and 3 and 6 months following first injections (solid columns) compared with placebo (hatched columns). Data presented as mean ± standard error. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Pain measured as visual analogue scale (VAS) at baseline and 3 and 6 months following first injections (solid columns) compared with placebo (hatched columns). Data presented as mean ± standard error. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

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