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The Mediterranean Diet, its Components, and Cardiovascular Disease

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Presentation on theme: "The Mediterranean Diet, its Components, and Cardiovascular Disease"— Presentation transcript:

1 The Mediterranean Diet, its Components, and Cardiovascular Disease
R. Jay Widmer, MD, PhD, Andreas J. Flammer, MD, Lilach O. Lerman, MD, PhD, Amir Lerman, MD  The American Journal of Medicine  Volume 128, Issue 3, Pages (March 2015) DOI: /j.amjmed Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Estimates of risk ratio reduction based on recent meta-analyses of trials examining medication adherence vs placebo and lifestyle interventions vs control. Estimates on the effect of niacin were removed as there are no recent meta-analyses that include recent negative data. Relative risks are reported with logarithmic conversions and standard errors plotted on the Forest plot. Estimates of lifestyle modifications such as the Mediterranean diet as a whole,12 fruits and vegetables,3-5 smoking cessation,9 moderate alcohol,11 omega-3 fatty acids,16 and improved physical activity8 have substantial benefits for CVD prevention not seen with commonly used standard medical therapies such as statins,6,7 renin-angiotensin system blockade,10 fibrates,13 aspirin,14 and beta-blockers.15 The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions

3 Figure 2 Collective mechanisms proposed to underlie the protective effect of foods against cardiovascular disease. Clearly, no single ingredient or mechanism can account for all the advantages of certain food groups, and it takes a calorically sensible and balanced variety to derive the greatest benefit for patients. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions


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