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Determination of IgE and IgG reactivity to more than 170 allergen molecules in paper- dried blood spots  Victoria Garib, MD, PhD, Eva Rigler, MD, PhD,

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Presentation on theme: "Determination of IgE and IgG reactivity to more than 170 allergen molecules in paper- dried blood spots  Victoria Garib, MD, PhD, Eva Rigler, MD, PhD,"— Presentation transcript:

1 Determination of IgE and IgG reactivity to more than 170 allergen molecules in paper- dried blood spots  Victoria Garib, MD, PhD, Eva Rigler, MD, PhD, Felix Gastager, Eng, Raffaela Campana, PhD, Yulia Dorofeeva, MD, Pia Gattinger, MSc, Yury Zhernov, MD, PhD, Musa Khaitov, MD, PhD, Rudolf Valenta, MD  Journal of Allergy and Clinical Immunology  Volume 143, Issue 1, Pages (January 2019) DOI: /j.jaci Copyright © 2018 The Authors Terms and Conditions

2 Fig 1 Correlations of allergen-specific IgE levels measured in fresh serum of an allergic patient (#18, Table E2) with IgE levels measured in serum samples recovered immediately and after 1 week storage at +37°C, +22°C, +4°C, and −20°C. Correlations are shown for the 21 recognized allergens in scatter plots with r and P values. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2018 The Authors Terms and Conditions

3 Fig 2 Screen-shots of IgG reactivity to micro-arrayed allergens in (A) a fresh serum sample and in (B-D) immediately recovered eluates from 3 identically prepared paper-dried blood spots. E, Scatter plot of the correlations of allergen-specific IgG levels with r and P values for the 48 recognized allergens (Table E4). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2018 The Authors Terms and Conditions

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