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Imbalance of coagulation and fibrinolysis can predict vascular access failure in patients on hemodialysis after vascular access intervention  Yukiko Hasuike,

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Presentation on theme: "Imbalance of coagulation and fibrinolysis can predict vascular access failure in patients on hemodialysis after vascular access intervention  Yukiko Hasuike,"— Presentation transcript:

1 Imbalance of coagulation and fibrinolysis can predict vascular access failure in patients on hemodialysis after vascular access intervention  Yukiko Hasuike, MD, PhD, Naoto Kakita, MD, Makoto Aichi, MD, Satoko Masachika, MD, Mari Kantou, MD, Shoko Ikeda Takahashi, MD, Masayoshi Nanami, MD, PhD, Yasuyuki Nagasawa, MD, PhD, Takahiro Kuragano, MD, PhD, Takeshi Nakanishi, MD, PhD  Journal of Vascular Surgery  Volume 69, Issue 1, Pages e2 (January 2019) DOI: /j.jvs Copyright © 2018 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Flow diagram for selection of patients. ESA, Erythropoiesis-stimulating agent; MHD, maintenance hemodialysis; TAT, thrombin-antithrombin complex. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2018 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Kaplan-Meier analyses of patency rates after vascular access (VA) intervention. Access failure-free survival of VA stratified by flow volume (A), type of VA (B), and thrombin-antithrombin complex (TAT)/plasmin-α2-plasmin inhibitor complex (PIC) ratio (C). A, Kaplan-Meier analysis between patients with high flow volume (FV; ≥344 mL/min; n = 239) and low flow volume (<344 mL/min; n = 223). B, Kaplan-Meier analysis between patients with native arteriovenous fistula (n = 352) and arteriovenous graft (n = 110). C, Kaplan-Meier analysis between patients with low TAT/PIC ratio (<4.17/103; n = 393) and high TAT/PIC ratio (≥4.17/103; n = 69). Number at risk is indicated below the graph. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2018 Society for Vascular Surgery Terms and Conditions

4 Supplementary Fig 1 (online only)
Receiver operating characteristic (ROC) curves for flow volume (left) and thrombin-antithrombin complex (TAT)/plasmin-α2-plasmin inhibitor complex (PIC) ratio (right). Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2018 Society for Vascular Surgery Terms and Conditions

5 Supplementary Fig 2 (online only)
Kaplan-Meier analyses of patency rates of patients with arteriovenous fistula (AVF; A) and arteriovenous graft (AVG; B). Access failure-free survival of vascular access (VA) stratified by flow volume and thrombin-antithrombin complex (TAT)/plasmin-α2-plasmin inhibitor complex (PIC) ratio. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2018 Society for Vascular Surgery Terms and Conditions

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