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Hywel C. Williams, Robert P. Dellavalle 

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Presentation on theme: "Hywel C. Williams, Robert P. Dellavalle "— Presentation transcript:

1 The Growth of Clinical Trials and Systematic Reviews in Informing Dermatological Patient Care 
Hywel C. Williams, Robert P. Dellavalle  Journal of Investigative Dermatology  Volume 132, Issue 3, Pages (March 2012) DOI: /jid Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Atopic dermatitis is a chronic disease in most sufferers, yet the majority of clinical trials have looked at short-term outcomes of ≤6 weeks (Hoareet al., 2000). Photograph used with permission. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Annual citations of meta-analyses in PubMed are growing at a rate almost three times faster than that of all publication types in PubMed. Source: accessed 24 June 2011. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 File drawers have become the final resting place for many studies with nonsignificant results. Reproduced with permission. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

5 Figure 4 Research wastage can occur at several stages along the research development pathway. Reproduced with permission from Chalmers and Glasziou (2009). Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions


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