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A patient with improvement of ulcerative colitis after appendectomy
Kazuichi Okazaki, Hisashi Onodera, Norihiko Watanabe, Hiroshi Nakase, Suguru Uose, Mitsunobu Matsushita, Chiharu Kawanami, Masayuki Imamura, Tsutomu Chiba Gastroenterology Volume 119, Issue 2, Pages (August 2000) DOI: /gast Copyright © 2000 American Gastroenterological Association Terms and Conditions
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Fig. 1 Colonoscopic findings. Colonoscopic examination showed (A) diffusely edematous, inflammatory mucosa with ulcers in the rectum and (B) skipped erosions in the orifice of the appendix. One month after appendectomy, colonoscopic findings had improved remarkably, with no erosions or redness in the (C) rectum and (D) cecum. Three years after appendectomy, colonoscopic findings showed an inactive state in the (E) rectum and (F) cecum. Gastroenterology , DOI: ( /gast ) Copyright © 2000 American Gastroenterological Association Terms and Conditions
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Fig. 2 Microscopic findings. (A) Before the appendectomy, there was remarkable infiltration of mononuclear cells in the rectal mucosa, which was diagnosed as a grade IV in Matt's classification. (B) Microscopic findings of the appendix showed moderate appendicitis, with mucosal erosions and moderate infiltration of lymphocytes. (C) One month after appendectomy, inflammation in the rectal mucosa had improved remarkably and was diagnosed as grade III in Matt's classification. (D) Three years after appendectomy, biopsy specimens from the rectal mucosa showed grade II in Matt's classification. (H&E staining; original magnifications: A, C, and D, 125×; B, 50×.) Gastroenterology , DOI: ( /gast ) Copyright © 2000 American Gastroenterological Association Terms and Conditions
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