1. Volume 75, Issue 1, Pages 60-71 (January 2009)
A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia 
Nadezda Koleganova, Grzegorz Piecha, Eberhard Ritz, Claus Peter Schmitt, Marie-Luise Gross 
Kidney International 
Volume 75, Issue 1, Pages (January 2009)
DOI: /ki
Copyright © 2009 International Society of Nephrology Terms and Conditions

2. Figure 1
Hystology of the aorta. Thickness of aortic (a) intima and (b) media. aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

3. Figure 2
Calcium deposits in the media of the aorta. aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

4. Figure 3
Hystology of the aorta. Expression of calcium-sensing receptor (CaSR) in aortic (a) intima and (b) media by immunohistochemistry and in aortic tissue by (c) Western blot. Representative examples of immune staining of aorta from (d) sham-op+vehicle, (e) sham-op+R-568, (f) sham-op+calcitriol, (g) SNX+vehicle, (h) SNX+R-568, and (i) SNX+calcitriol. Magnification × 400. Staining in calcified regions (inserts).
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

5. Figure 4
Hystology of the aorta. Expression of CaSR in intramyocardial arteries in the (a) intima and (b) media by in situ hybridization.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

6. Figure 5
Hystology of the aorta. Immune staining for PCNA in the aorta: values for (a) intima, (b) media aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568; representative examples of (c) sham-op+vehicle, (d) SNX+vehicle, (e) sham-op+R-568, (f) SNX+R-568, (g) sham-op+calcitriol, and (h) SNX+calcitriol. Magnification × 400.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

7. Figure 6
Hystology of the aorta. Immune staining for cbfa-1 in the aorta: values for (a) intima, (b) media aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568; representative examples of (c) sham-op+vehicle, (d) SNX+vehicle, (e) sham-op+R-568, (f) SNX+R-568, (g) sham-op+calcitriol, and (h) SNX+calcitriol. Magnification × 400.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

8. Figure 7
Hystology of the aorta. Immune staining for osteonectin in the aorta: values for (a) intima, (b) media aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568; representative examples of (c) sham-op+vehicle, (d) SNX+vehicle, (e) sham-op+R-568, (f) SNX+R-568, (g) sham-op+calcitriol, and (h) SNX+calcitriol. Magnification × 400.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions

9. Figure 8
Representative Western blots of aortic tissue (a–i). The values of sham-op+vehicle were taken as reference (100%). aP<0.05 vs sham+vehicle; bP<0.05 vs sham+R-568; cP<0.05 vs sham+calcitriol; dP<0.05 vs SNX+vehicle; eP<0.05 vs SNX+R-568.
Kidney International  , 60-71DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions