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Specificities of Lung Adenocarcinoma in Women Who Have Never Smoked

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Presentation on theme: "Specificities of Lung Adenocarcinoma in Women Who Have Never Smoked"— Presentation transcript:

1 Specificities of Lung Adenocarcinoma in Women Who Have Never Smoked
Julien Mazières, MD, PhD, Isabelle Rouquette, MD, Benoit Lepage, MD, Julie Milia, PhD, Laurent Brouchet, MD, PhD, Nicolas Guibert, MD, Michèle Beau-Faller, MD, PhD, Pierre Validire, MD, PhD, Paul Hofman, MD, PhD, Pierre Fouret, MD, PhD  Journal of Thoracic Oncology  Volume 8, Issue 7, Pages (July 2013) DOI: /JTO.0b013e dfb Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Immunohistochemistry of hormonal tumor staining (scale magnitude ×400). A, ERα staining of lung tumor tissue (× 400) (F10). Nucleus score is +++, cytoplasm score is ++; (B), ERβ staining of lung tumor tissue (× 400). ERβ score is 6 (A). ER, estrogen receptor. Journal of Thoracic Oncology 2013 8, DOI: ( /JTO.0b013e dfb) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Biomarker incidence in women who have never smoked (shaded) versus women smokers (lined). p < for EGFR mutation, p = for K-Ras mutation, and p = for ERα. EGFR, epidermal growth factor receptor; ER, estrogen receptor; PR, progesterone receptors. Journal of Thoracic Oncology 2013 8, DOI: ( /JTO.0b013e dfb) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

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