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Impact of pituitary suppression on antral follicle count and oocyte recovery after ovarian stimulation  Nam D. Tran, M.D., Ph.D., Lusine Aghajanova, M.D.,

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Presentation on theme: "Impact of pituitary suppression on antral follicle count and oocyte recovery after ovarian stimulation  Nam D. Tran, M.D., Ph.D., Lusine Aghajanova, M.D.,"— Presentation transcript:

1 Impact of pituitary suppression on antral follicle count and oocyte recovery after ovarian stimulation  Nam D. Tran, M.D., Ph.D., Lusine Aghajanova, M.D., Ph.D., Chia-Ning Kao, M.S., Marcelle I. Cedars, M.D., Mitchell P. Rosen, M.D.  Fertility and Sterility  Volume 105, Issue 3, Pages (March 2016) DOI: /j.fertnstert Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Impact of short-term pituitary suppression on antral follicle count (AFC) and number of oocytes retrieved. A significant decrease in AFC after pituitary suppression (suppressed AFC) was observed in all treatment groups. Nonetheless, this decrease in AFC did not compromise the number of oocytes recovered after pituitary suppression, as both baseline and suppressed AFC were significant predictors of number of oocytes retrieved. GnRHa = GnRH agonist; OCP = oral contraceptive pills. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Age, baseline antral follicle count (AFC), and hormones independently affect the decrease in AFC after pituitary suppression. These plots demonstrate the theoretical predicted decrease in AFC after pituitary suppression in women between 30 and 49 years old taking E2 (estradiol), GnRH-a (GnRH agonist), OC pills (OCP), or OCP/GnRH-a. Negative value of Y-axis demonstrates the decrease in AFC after pituitary suppression factoring age and baseline AFC. (A) Theoretical model for patients with AFC ≤10. (B) Theoretical model for patients with AFC ≥11. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions


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