Presentation is loading. Please wait.

Presentation is loading. Please wait.

Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma  Benny Dua, MSc, Richard M. Watson, BSc,

Published byMarybeth Ellis Modified over 5 years ago

Similar presentations

Presentation on theme: "Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma  Benny Dua, MSc, Richard M. Watson, BSc,"— Presentation transcript:

1 Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma  Benny Dua, MSc, Richard M. Watson, BSc, Gail M. Gauvreau, PhD, Paul M. O'Byrne, MB  Journal of Allergy and Clinical Immunology  Volume 126, Issue 1, Pages (July 2010) DOI: /j.jaci Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Gating strategy for enumeration of DCs. A, Mononuclear gate R1 is set up around the mononuclear cell population on the SSC versus CD45 plot and then transferred to a Lin1 vs HLA-DR plot to identify DC populations (R2). B, Gating around the mDC population (R3). C, Gating around the pDC population (R4). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Kinetics of sputum mDCs (A) and pDCs (B) after inhalation of diluent versus allergen. ∗Difference between baseline and 24 hours postallergen measurements at P < .05; ∗∗difference between diluent and allergen measurements at P < .05. Data are presented as means ± SEMs. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig. 3 Expression of CCR6 and CCR7 on mDCs (A) and pDCs (B) compared with their isotype controls. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig 4 Kinetics of sputum supernatant levels of MIP-3α (A) and MIP-3β (B) after inhalation of diluent versus allergen. ∗Difference between baseline and 24 hours postallergen measurements at P < .05. Data are presented as means ± SEMs. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Download ppt "Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma  Benny Dua, MSc, Richard M. Watson, BSc,"

Similar presentations

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.

Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
Vitamin D3 treatment of vitamin D–insufficient asthmatic patients does not alter immune cell function  Brandy Reid, MS, Pierre-Olivier Girodet, MD, PhD,

Vitamin D3 treatment of vitamin D–insufficient asthmatic patients does not alter immune cell function  Brandy Reid, MS, Pierre-Olivier Girodet, MD, PhD,
Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia  Steven.

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia  Steven.
Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses  Chris J. Corrigan, MD, PhD, Wei.

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses  Chris J. Corrigan, MD, PhD, Wei.
The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy  Jennifer M. Maloney, MD, Magnus Rudengren, BSc, Staffan.

The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy  Jennifer M. Maloney, MD, Magnus Rudengren, BSc, Staffan.
Allergen immunotherapy: A practice parameter third update

Allergen immunotherapy: A practice parameter third update
Plasmacytoid dendritic cell depletion in DOCK8 deficiency: Rescue of severe herpetic infections with IFN-α 2b therapy  Sevgi Keles, MD, Haifa H. Jabara,

Plasmacytoid dendritic cell depletion in DOCK8 deficiency: Rescue of severe herpetic infections with IFN-α 2b therapy  Sevgi Keles, MD, Haifa H. Jabara,
Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression  Michiko K. Oyoshi,

Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression  Michiko K. Oyoshi,
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Timely follow-up of a GATA2 deficiency patient allows successful treatment  Sara Ciullini Mannurita, MSc, Marina Vignoli, PhD, Gloria Colarusso, MD, PhD,

Timely follow-up of a GATA2 deficiency patient allows successful treatment  Sara Ciullini Mannurita, MSc, Marina Vignoli, PhD, Gloria Colarusso, MD, PhD,
Is 9 more than 2 also in allergic airway inflammation?

Is 9 more than 2 also in allergic airway inflammation?
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
Jeff Choi, BSc, Rosemary Fernandez, PhD, Holden T

Jeff Choi, BSc, Rosemary Fernandez, PhD, Holden T
Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma  Takashi Kinoshita, MD, Adrian Baatjes, MSc,

Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma  Takashi Kinoshita, MD, Adrian Baatjes, MSc,
Zuhair K. Ballas, MD  Journal of Allergy and Clinical Immunology 

Zuhair K. Ballas, MD  Journal of Allergy and Clinical Immunology 
Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses  Chris J. Corrigan, MD, PhD, Wei.

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses  Chris J. Corrigan, MD, PhD, Wei.
Toll-like receptor 9 suppression in plasmacytoid dendritic cells after IgE-dependent activation is mediated by autocrine TNF-α  John T. Schroeder, PhD,

Toll-like receptor 9 suppression in plasmacytoid dendritic cells after IgE-dependent activation is mediated by autocrine TNF-α  John T. Schroeder, PhD,

Similar presentations

Ads by Google