1. Prolonged Thrombocytopenia Following Allogeneic Hematopoietic Stem Cell Transplantation and Its Association with a Reduction in Ploidy and an Immaturation of Megakaryocytes 
Xiaohui Zhang, Haixia Fu, Lanping Xu, Daihong Liu, Jianzhong Wang, Kaiyan Liu, Xiaojun Huang 
Biology of Blood and Marrow Transplantation 
Volume 17, Issue 2, Pages (February 2011)
DOI: /j.bbmt
Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

2. Figure 1
The megakaryocyte ploidy distribution pattern of the 3 groups (shown as the means of the relative frequency and standard deviation). (A) The allo-HSCT patients with prolonged thrombocytopenia (n = 32); (B) The allo-HSCT patients without prolonged thrombocytopenia (n = 27). (C) The group of healthy volunteers (n = 13). The modal megakaryocyte of healthy volunteers ploidy is 16N. The megakaryocyte ploidy distribution in the allo-HSCT patients, especially in the patients with prolonged thrombocytopenia, exhibited a significant shift to low ploidy cells (left shift), with a marked increase in 2N to 8N cells and a reciprocal decrease in 16N to 64N cells.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions