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Differences in muscarinic-receptor agonist–, oxytocin-, and prostaglandin-induced uterine contractions  Ralf Dittrich, Ph.D., Andreas Mueller, M.D., Patricia.

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Presentation on theme: "Differences in muscarinic-receptor agonist–, oxytocin-, and prostaglandin-induced uterine contractions  Ralf Dittrich, Ph.D., Andreas Mueller, M.D., Patricia."— Presentation transcript:

1 Differences in muscarinic-receptor agonist–, oxytocin-, and prostaglandin-induced uterine contractions  Ralf Dittrich, Ph.D., Andreas Mueller, M.D., Patricia G. Oppelt, M.D., Inge Hoffmann, Matthias W. Beckmann, M.D., Theodoros Maltaris, M.D.  Fertility and Sterility  Volume 92, Issue 5, Pages (November 2009) DOI: /j.fertnstert Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Swine uterus. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Increases in intrauterine pressure (IUP), shown as mean and SD, after administration of increasing dosages of oxytocin. A dose-dependent increase in IUP was observed in the isthmus uteri (P<.001) and corpus uteri (P<.001) after oxytocin administration. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Increases in intrauterine pressure (IUP), shown as mean and SD, after administration of increasing dosages of prostaglandins E1, E2, and F2α. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

5 Figure 4 Increases in intrauterine pressure (IUP), shown as mean and SD after administration of increasing dosages of carbachol. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

6 Figure 5 A typical pressure profile after administration of carbachol (10-μmol/L bolus) in the isthmus region (blue line) and the corpus region (magenta line). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions


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