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Calmodulin in Action Cell

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Presentation on theme: "Calmodulin in Action Cell"— Presentation transcript:

1 Calmodulin in Action Cell
Klaus P. Hoeflich, Mitsuhiko Ikura  Cell  Volume 108, Issue 6, Pages (March 2002) DOI: /S (02)

2 Figure 1 Comparison of Different Calmodulin-Target Structures
The Protein Data Bank accession code for Ca2+-CaM alone is 1CLL, and for CaM in complex with CaMKII, CaMKK, MLCK, Ca2+-activated K+ channel, and anthrax adenylyl cyclase are 1CDM, 1CKK, 1CDL, 1G4Y, and 1K93, respectively. CaM is shown in yellow and calcium ions are depicted in blue. Cell  , DOI: ( /S (02) )

3 Figure 2 Protein Activation Mechanisms by Calmodulin
(A) Relieving autoinhibition. (B) Active site remodeling. (C) Dimerization. Calcium ions are depicted in yellow, and active sites by asterisks. Cell  , DOI: ( /S (02) )


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