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Curbing Tregs’ (Lack of) Enthusiasm

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1 Curbing Tregs’ (Lack of) Enthusiasm
Taha Merghoub, Jedd D. Wolchok  Cell  Volume 169, Issue 6, Pages (June 2017) DOI: /j.cell Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Impact of NRP1-Deficient Tregs on WT Tregs
WT Tregs are suppressive, and Nrp1−/− Tregs lose their suppressive ability while maintaining Foxp3 expression. When Nrp1−/− Tregs are in the presence of WT Tregs, they impact their suppressive function. The crosstalk between these two types of Tregs is interferon gamma dependent. Cell  , DOI: ( /j.cell ) Copyright © 2017 Elsevier Inc. Terms and Conditions


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