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Combined Use of the Novel Biomarkers High-Sensitivity Troponin T and ST2 for Heart Failure Risk Stratification vs Conventional Assessment  Josep Lupón,

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Presentation on theme: "Combined Use of the Novel Biomarkers High-Sensitivity Troponin T and ST2 for Heart Failure Risk Stratification vs Conventional Assessment  Josep Lupón,"— Presentation transcript:

1 Combined Use of the Novel Biomarkers High-Sensitivity Troponin T and ST2 for Heart Failure Risk Stratification vs Conventional Assessment  Josep Lupón, MD, PhD, Marta de Antonio, MD, Amparo Galán, MD, PhD, Joan Vila, MSc, Elisabet Zamora, MD, PhD, Agustín Urrutia, MD, PhD, Antoni Bayes-Genis, MD, PhD  Mayo Clinic Proceedings  Volume 88, Issue 3, Pages (March 2013) DOI: /j.mayocp Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Kaplan-Meier survival curves according to biomarkers. A, Survival according to high-sensitivity cardiac troponin T (hs-cTnT) and high-sensitivity soluble ST2 (hs-ST2) levels (above or below the cutoff points). B, Survival according to N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (above or below the cutoff point) in patients with either hs-cTnT or hs-ST2 levels below the cutoff points (left) and in patients with hs-cTnT and hs-ST2 levels above the cutoff points (right). Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 1 Kaplan-Meier survival curves according to biomarkers. A, Survival according to high-sensitivity cardiac troponin T (hs-cTnT) and high-sensitivity soluble ST2 (hs-ST2) levels (above or below the cutoff points). B, Survival according to N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (above or below the cutoff point) in patients with either hs-cTnT or hs-ST2 levels below the cutoff points (left) and in patients with hs-cTnT and hs-ST2 levels above the cutoff points (right). Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 2 Crude mortality rates during follow-up. The presence of any biomarker above the cutoff point (from 0 to 3) is shown on the x-axis. The blue bar illustrates the high-sensitivity cardiac troponin T (hs-TnT) + high-sensitivity soluble ST2 (hs-ST2) combination above the cutoff points. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions


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